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Segmentation and Classification of Pap Smear Images for Cervical Cancer Detection Using Deep Learning
Albzour, Nisreen, Lam, Sarah S.
Cervical cancer remains a significant global health concern and a leading cause of cancer-related deaths among women. Early detection through Pap smear tests is essential to reduce mortality rates; however, the manual examination is time consuming and prone to human error. This study proposes a deep learning framework that integrates U-Net for segmentation and a classification model to enhance diagnostic performance. The Herlev Pap Smear Dataset, a publicly available cervical cell dataset, was utilized for training and evaluation. The impact of segmentation on classification performance was evaluated by comparing the model trained on segmented images and another trained on non-segmented images. Experimental results showed that the use of segmented images marginally improved the model performance on precision (about 0.41 percent higher) and F1-score (about 1.30 percent higher), which suggests a slightly more balanced classification performance. While segmentation helps in feature extraction, the results showed that its impact on classification performance appears to be limited. The proposed framework offers a supplemental tool for clinical applications, which may aid pathologists in early diagnosis.
Disentangled Object-Centric Image Representation for Robotic Manipulation
Emukpere, David, Deffayet, Romain, Wu, Bingbing, Brรฉgier, Romain, Niemaz, Michael, Meunier, Jean-Luc, Proux, Denys, Renders, Jean-Michel, Kim, Seungsu
Learning robotic manipulation skills from vision is a promising approach for developing robotics applications that can generalize broadly to real-world scenarios. As such, many approaches to enable this vision have been explored with fruitful results. Particularly, object-centric representation methods have been shown to provide better inductive biases for skill learning, leading to improved performance and generalization. Nonetheless, we show that object-centric methods can struggle to learn simple manipulation skills in multi-object environments. Thus, we propose DOCIR, an object-centric framework that introduces a disentangled representation for objects of interest, obstacles, and robot embodiment. We show that this approach leads to state-of-the-art performance for learning pick and place skills from visual inputs in multi-object environments and generalizes at test time to changing objects of interest and distractors in the scene. Furthermore, we show its efficacy both in simulation and zero-shot transfer to the real world.
Single cell resolution 3D imaging and segmentation within intact live tissues
Paci, G., Vicente-Munuera, P., Fernandez-Mosquera, I., Miranda, A., Lau, K., Zhang, Q., Barrientos, R., Mao, Y.
Epithelial cells form diverse structures from squamous spherical organoids to densely packed pseudostratified folded tissues. Quantification of cellular properties in these contexts requires high-resolution deep imaging and computational techniques to achieve truthful threedimensional (3D) structural features. Here, we describe a detailed step-by-step protocol for sample preparation, imaging and deep-learning-assisted cell segmentation to achieve accurate quantification of fluorescently labelled individual cells in 3D within live tissues. We share the "lessons learned" through troubleshooting 3D imaging of Drosophila wing discs, including considerations on the choice of microscopy modality and settings (objective, sample mounting) and available segmentation methods. In addition, we include a computational pipeline alongside custom code to assist replication of the protocol. While we focus on the segmentation of cell outlines from membrane labelling, this protocol applies to a wide variety of samples, and we believe it will be valuable for studying other tissues that demand complex analysis in 3D.
Super-Resolution of 3D Micro-CT Images Using Generative Adversarial Networks: Enhancing Resolution and Segmentation Accuracy
Ugolkov, Evgeny, He, Xupeng, Kwak, Hyung, Hoteit, Hussein
We develop a procedure for substantially improving the quality of segmented 3D micro-Computed Tomography (micro-CT) images of rocks with a Machine Learning (ML) Generative Model. The proposed model enhances the resolution eightfold (8x) and addresses segmentation inaccuracies due to the overlapping X-ray attenuation in micro-CT measurement for different rock minerals and phases. The proposed generative model is a 3D Deep Convolutional Wasserstein Generative Adversarial Network with Gradient Penalty (3D DC WGAN-GP). The algorithm is trained on segmented 3D low-resolution micro-CT images and segmented unpaired complementary 2D high-resolution Laser Scanning Microscope (LSM) images. The algorithm was demonstrated on multiple samples of Berea sandstones. We achieved high-quality super-resolved 3D images with a resolution of 0.4375 micro-m/voxel and accurate segmentation for constituting minerals and pore space. The described procedure can significantly expand the modern capabilities of digital rock physics.
Improving Sickle Cell Disease Classification: A Fusion of Conventional Classifiers, Segmented Images, and Convolutional Neural Networks
Cardoso, Victor Jรบnio Alcรขntara, Moreira, Rodrigo, Mari, Joรฃo Fernando, Moreira, Larissa Ferreira Rodrigues
Sickle cell anemia, which is characterized by abnormal erythrocyte morphology, can be detected using microscopic images. Computational techniques in medicine enhance the diagnosis and treatment efficiency. However, many computational techniques, particularly those based on Convolutional Neural Networks (CNNs), require high resources and time for training, highlighting the research opportunities in methods with low computational overhead. In this paper, we propose a novel approach combining conventional classifiers, segmented images, and CNNs for the automated classification of sickle cell disease. We evaluated the impact of segmented images on classification, providing insight into deep learning integration. Our results demonstrate that using segmented images and CNN features with an SVM achieves an accuracy of 96.80%. This finding is relevant for computationally efficient scenarios, paving the way for future research and advancements in medical-image analysis.
SegNet: A Segmented Deep Learning based Convolutional Neural Network Approach for Drones Wildfire Detection
Jonnalagadda, Aditya V., Hashim, Hashim A.
This research addresses the pressing challenge of enhancing processing times and detection capabilities in Unmanned Aerial Vehicle (UAV)/drone imagery for global wildfire detection, despite limited datasets. Proposing a Segmented Neural Network (SegNet) selection approach, we focus on reducing feature maps to boost both time resolution and accuracy significantly advancing processing speeds and accuracy in real-time wildfire detection. This paper contributes to increased processing speeds enabling real-time detection capabilities for wildfire, increased detection accuracy of wildfire, and improved detection capabilities of early wildfire, through proposing a new direction for image classification of amorphous objects like fire, water, smoke, etc. Employing Convolutional Neural Networks (CNNs) for image classification, emphasizing on the reduction of irrelevant features vital for deep learning processes, especially in live feed data for fire detection. Amidst the complexity of live feed data in fire detection, our study emphasizes on image feed, highlighting the urgency to enhance real-time processing. Our proposed algorithm combats feature overload through segmentation, addressing challenges arising from diverse features like objects, colors, and textures. Notably, a delicate balance of feature map size and dataset adequacy is pivotal. Several research papers use smaller image sizes, compromising feature richness which necessitating a new approach. We illuminate the critical role of pixel density in retaining essential details, especially for early wildfire detection. By carefully selecting number of filters during training, we underscore the significance of higher pixel density for proper feature selection. The proposed SegNet approach is rigorously evaluated using real-world dataset obtained by a drone flight and compared to state-of-the-art literature.
Navigating the Synthetic Realm: Harnessing Diffusion-based Models for Laparoscopic Text-to-Image Generation
Allmendinger, Simeon, Hemmer, Patrick, Queisner, Moritz, Sauer, Igor, Mรผller, Leopold, Jakubik, Johannes, Vรถssing, Michael, Kรผhl, Niklas
Recent advances in synthetic imaging open up opportunities for obtaining additional data in the field of surgical imaging. This data can provide reliable supplements supporting surgical applications and decision-making through computer vision. Particularly the field of image-guided surgery, such as laparoscopic and robotic-assisted surgery, benefits strongly from synthetic image datasets and virtual surgical training methods. Our study presents an intuitive approach for generating synthetic laparoscopic images from short text prompts using diffusion-based generative models. We demonstrate the usage of state-of-the-art text-to-image architectures in the context of laparoscopic imaging with regard to the surgical removal of the gallbladder as an example. Results on fidelity and diversity demonstrate that diffusion-based models can acquire knowledge about the style and semantics in the field of image-guided surgery. A validation study with a human assessment survey underlines the realistic nature of our synthetic data, as medical personnel detects actual images in a pool with generated images causing a false-positive rate of 66%. In addition, the investigation of a state-of-the-art machine learning model to recognize surgical actions indicates enhanced results when trained with additional generated images of up to 5.20%. Overall, the achieved image quality contributes to the usage of computer-generated images in surgical applications and enhances its path to maturity.
Eye Disease Prediction using Ensemble Learning and Attention on OCT Scans
Naik, Gauri, Narvekar, Nandini, Agarwal, Dimple, Nandanwar, Nishita, Pande, Himangi
Eye diseases have posed significant challenges for decades, but advancements in technology have opened new avenues for their detection and treatment. Machine learning and deep learning algorithms have become instrumental in this domain, particularly when combined with Optical Coherent Technology (OCT) imaging. We propose a novel method for efficient detection of eye diseases from OCT images. Our technique enables the classification of patients into disease free (normal eyes) or affected by specific conditions such as Choroidal Neovascularization (CNV), Diabetic Macular Edema (DME), or Drusen. In this work, we introduce an end to end web application that utilizes machine learning and deep learning techniques for efficient eye disease prediction. The application allows patients to submit their raw OCT scanned images, which undergo segmentation using a trained custom UNet model. The segmented images are then fed into an ensemble model, comprising InceptionV3 and Xception networks, enhanced with a self attention layer. This self attention approach leverages the feature maps of individual models to achieve improved classification accuracy. The ensemble model's output is aggregated to predict and classify various eye diseases. Extensive experimentation and optimization have been conducted to ensure the application's efficiency and optimal performance. Our results demonstrate the effectiveness of the proposed approach in accurate eye disease prediction. The developed web application holds significant potential for early detection and timely intervention, thereby contributing to improved eye healthcare outcomes.
Grain and Grain Boundary Segmentation using Machine Learning with Real and Generated Datasets
Warren, Peter, Raju, Nandhini, Prasad, Abhilash, Hossain, Shajahan, Subramanian, Ramesh, Kapat, Jayanta, Manjooran, Navin, Ghosh, Ranajay
We report significantly improved accuracy of grain boundary segmentation using Convolutional Neural Networks (CNN) trained on a combination of real and generated data. Manual segmentation is accurate but time-consuming, and existing computational methods are faster but often inaccurate. To combat this dilemma, machine learning models can be used to achieve the accuracy of manual segmentation and have the efficiency of a computational method. An extensive dataset of from 316L stainless steel samples is additively manufactured, prepared, polished, etched, and then microstructure grain images were systematically collected. Grain segmentation via existing computational methods and manual (by-hand) were conducted, to create "real" training data. A Voronoi tessellation pattern combined with random synthetic noise and simulated defects, is developed to create a novel artificial grain image fabrication method. This provided training data supplementation for data-intensive machine learning methods. The accuracy of the grain measurements from microstructure images segmented via computational methods and machine learning methods proposed in this work are calculated and compared to provide much benchmarks in grain segmentation. Over 400 images of the microstructure of stainless steel samples were manually segmented for machine learning training applications. This data and the artificial data is available on Kaggle.
StawGAN: Structural-Aware Generative Adversarial Networks for Infrared Image Translation
Sigillo, Luigi, Grassucci, Eleonora, Comminiello, Danilo
This paper addresses the problem of translating night-time thermal infrared images, which are the most adopted image modalities to analyze night-time scenes, to daytime color images (NTIT2DC), which provide better perceptions of objects. We introduce a novel model that focuses on enhancing the quality of the target generation without merely colorizing it. The proposed structural aware (StawGAN) enables the translation of better-shaped and high-definition objects in the target domain. We test our model on aerial images of the DroneVeichle dataset containing RGB-IR paired images. The proposed approach produces a more accurate translation with respect to other state-of-the-art image translation models. The source code is available at https://github.com/LuigiSigillo/StawGAN